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Leukocytes are one type of Blood cells, the other two being Red blood cells and Platelets. Until now, information given by most Hematology Automated analysers on Leukocytes used for the complete blood count has only been numerical, reporting the total amount of Leukocytes and the percentage and absolute number of the different types thereof: Neutrophils, Lymphocytes, Monocytes, Eosinophils and Basophils (Diff Data). @Cell Population Data (CPD) are numerical data developed through VCS technology (Volume, Conductivity, Scatter (Laser Light scattering))〔VCS patent (WO1988007198) MULTI-PART DIFFERENTIAL ANALYZING APPARATUS UTILIZING LIGHT SCATTER TECHNIQUES (US Patent US5125737) http://patentscope.wipo.int/search/en/detail.jsf;jsessionid=B67D818877BB07E38094375E8DF95983.wapp1?docId=WO1988007198&recNum=1&maxRec=&office=&prevFilter=&sortOption=&queryString=&tab=PCTDescription〕 3D cube on DxH800, LH780, LH750, LH500, and Gen *S instruments, that give information about the leukocytes analyzed, reporting their volume, Conductivity and light scatter and are displayed as part of the Diff Data results. These parameters have recently appeared in some hematology textbooks as New White Blood Cell Parameters.〔New White Cell Parameters. Dacie and Lewis Practical Haematology, 11th Edition Chapter 3, page 45, 2012. Barbara J. Bain, Imelda Bates, Mike A Laffan, S. Mitchell Lewis. ISBN 9780702034084. http://www.expertconsultbook.com/expertconsult/b/book.do?method=display&decorator=none&type=bookPage&eid=4-u1.0-B978-0-7020-3408-4..00003-5--s0375&isbn=978-0-7020-3408-4&hitTerms=%22observation+parameter%22%7C%22white+blood+cell%22%7C%22white+blood+cells%22%7C%22white+cell%22%7CLEUKOCYTES%7Cleucocyte%7Cleukocyte%7Cleukocytes%7Cnew%7Cnewer%7Cnewest%7Cparameter%7Cparameters&hitNum=1〕 Previously, @ CPD received different names by other authors, as Research Population Data, Positional Parameters and Investigation Screen Parameters. @CPD was originally used for service engineers to verify the optimal setup of White blood cell (WBC) subpopulations in the Hematology instruments. For each of the four main WBC populations: Neutrophils, Lymphocytes, Monocytes and Eosinophils, there are six values displayed about the Coordinates of these Cells in three-dimensional spaces: 1) Volume Mean and Standard deviation 2) Conductivity Mean and Standard deviation 3) Scatter Mean and Standard deviation. It has been said that when the Leukocytes are normal, these data are normal, but in the event of diseases, the number of Cells increases or decreases and frequently so with different properties, as size, internal Cell content etc. In addition, where Blood cells are not seen under normal circumstances, as myelocytes (Immature Neutrophil), results in these data frequently become abnormal. When Looking for changes in the value of these data, it is possible to flag (message in the results) the presence of an abnormal proportion of Cells or the presence of different types of Cells, that, after confirmed with FDA/IVD approved methods, may help in the screening/detection of diseases. Over the past few years, articles related to these new @Cell Population Data have appeared in different journals using the changes to these data for the screening/flagging of major diseases including: *Bacterial infections and sepsis * * * * * * * * * * *malaria * * * * *Dengue * * *Viral diseases * * *Megaloblastic anemia * * * * *Myelodysplastic Syndromes * * * * *Lymphoproliferative disorders * * * * * * *Differential diagnosis of Thrombocytosis * * The possibility of using these new data in the screening of several diseases, used as a suspect flag, opens the door to an easy and inexpensive way for medical check ups for the population at large, because these data come free with the complete blood count provided by Hematology Automated analysers. @CPD, @Cell Population Data are tests for Research or Laboratory Use Only, and can not be reported to the physicians, only to be used as a suspect message, for the detection / suspect of abnormal cells. ==References== 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Cell Population Data」の詳細全文を読む スポンサード リンク
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